Global metabolomic and lipidomic analysis reveals the potential mechanisms of hemolysis effect of Ophiopogonin D and Ophiopogonin D' in vivo

Global metabolomic and lipidomic analysis reveals the potential mechanisms of hemolysis effect of Ophiopogonin D and Ophiopogonin D' in vivo

Abstract Background OPD and OPD' are the two main active components of Ophiopogon japonicas in Shenmai injection (SMI). Being isomers of each other, they are supposed to have similar pharmacological activities, but the actual situation is complicated. The difference of hemolytic behavior betwee...

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Bibliographic Details
Main Authors: Huan-Hua Xu, Zhen-Hong Jiang, Cong-Shu Huang, Yu-Ting Sun, Long-Long Xu, Xiang-Ling Tang, Hong-Ling Tan, Zeng-Chun Ma, Yue Gao
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Chinese Medicine
Subjects:
Hemolysis
Ophiopogonin D
Ophiopogonin D'
Metabolomic
Lipidomic
Online Access:https://doi.org/10.1186/s13020-020-00412-z

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