Upregulation of Heme Oxygenase-1 by Hemin Alleviates Sepsis-Induced Muscle Wasting in Mice

Upregulation of Heme Oxygenase-1 by Hemin Alleviates Sepsis-Induced Muscle Wasting in Mice

Hemin, an inducer of heme oxygenase-1 (HO-1), can enhance the activation of HO-1. HO-1 exhibits a variety of activities, such as anti-inflammatory, antioxidative, and antiapoptotic functions. The objective of this study was to investigate the effects of hemin on sepsis-induced skeletal muscle wastin...

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Bibliographic Details
Main Authors:	Xiongwei Yu, Wenjun Han, Changli Wang, Daming Sui, Jinjun Bian, Lulong Bo, Xiaoming Deng
Format:	Article
Language:	English
Published:	Hindawi Limited 2018-01-01
Series:	Oxidative Medicine and Cellular Longevity
Online Access:	http://dx.doi.org/10.1155/2018/8927104

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