Alda-1 treatment promotes the therapeutic effect of mitochondrial transplantation for myocardial ischemia-reperfusion injury

Alda-1 treatment promotes the therapeutic effect of mitochondrial transplantation for myocardial ischemia-reperfusion injury

Mitochondrial damage is a critical driver in myocardial ischemia-reperfusion (I/R) injury and can be alleviated via the mitochondrial transplantation. The efficiency of mitochondrial transplantation is determined by mitochondrial vitality. Because aldehyde dehydrogenase 2 (ALDH2) has a key role in r...

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Bibliographic Details
Main Authors: Xiaolei Sun, Rifeng Gao, Wenjia Li, Yongchao Zhao, Heng Yang, Hang Chen, Hao Jiang, Zhen Dong, Jingjing Hu, Jin Liu, Yunzeng Zou, Aijun Sun, Junbo Ge
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2021-07-01
Series:Bioactive Materials
Subjects:
Ischemia-reperfusion
Mitochondrial transfer
ALDH2 activation
Myocardial injury
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X20303571

Internet

http://www.sciencedirect.com/science/article/pii/S2452199X20303571

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