TRIM26 Facilitates HSV-2 Infection by Downregulating Antiviral Responses through the IRF3 Pathway

TRIM26 Facilitates HSV-2 Infection by Downregulating Antiviral Responses through the IRF3 Pathway

Herpes simplex virus type 2 (HSV-2) is the primary cause of genital herpes which results in significant morbidity and mortality, especially in women, worldwide. HSV-2 is transmitted primarily through infection of epithelial cells at skin and mucosal surfaces. Our earlier work to examine interactions...

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Bibliographic Details
Main Authors: Tushar Dhawan, Muhammad Atif Zahoor, Nishant Heryani, Samuel Tekeste Workenhe, Aisha Nazli, Charu Kaushic
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Viruses
Subjects:
TRIM26
intrinsic immunity
interferon
ISG
HSV-2
epithelial cell
Online Access:https://www.mdpi.com/1999-4915/13/1/70

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