Expression of Tra2β in Cancer Cells as a Potential Contributory Factor to Neoplasia and Metastasis

Expression of Tra2β in Cancer Cells as a Potential Contributory Factor to Neoplasia and Metastasis

The splicing regulator proteins SRSF1 (also known as ASF/SF2) and SRSF3 (also known as SRP20) belong to the SR family of proteins and can be upregulated in cancer. The SRSF1 gene itself is amplified in some cancer cells, and cancer-associated changes in the expression of MYC also increase SRSF1 gene...

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Bibliographic Details
Main Authors:	Andrew Best, Caroline Dagliesh, Ingrid Ehrmann, Mahsa Kheirollahi-Kouhestani, Alison Tyson-Capper, David J. Elliott
Format:	Article
Language:	English
Published:	Hindawi Limited 2013-01-01
Series:	International Journal of Cell Biology
Online Access:	http://dx.doi.org/10.1155/2013/843781

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