Serotype specific epitopes identified by neutralizing antibodies underpin immunogenic differences in Enterovirus B
So far no vaccine or antiviral therapy is available for Echovirus 30 (E30) that causes aseptic meningitis. Here, the authors generate and characterise two E30-specific monoclonal antibodies that block binding of the virus to its attachment receptor CD55 and uncoating receptor FcRn, and determine the...
| Main Authors: | , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2020-09-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-020-18250-w |