SOD1 regulates ribosome biogenesis in KRAS mutant non-small cell lung cancer
The superoxide dismutase SOD1 is highly expressed in lung cancer but its role has not fully investigated yet. In this study, the authors demonstrate that SOD1 regulates ribosome biogenesis driving KRAS-driven lung tumorigenesis.
Bibliographic Details
| Main Authors: |
Xiaowen Wang,
Hong Zhang,
Russell Sapio,
Jun Yang,
Justin Wong,
Xin Zhang,
Jessie Y. Guo,
Sharon Pine,
Holly Van Remmen,
Hong Li,
Eileen White,
Chen Liu,
Megerditch Kiledjian,
Dimitri G. Pestov,
X. F. Steven Zheng |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2021-04-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-021-22480-x
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