Comparative Efficacy of Two Doses of Nebulized Colistimethate for the Eradication of Pseudomonas Aeruginosa in Children with Cystic Fibrosis

BACKGROUND: Cystic fibrosis (CF) affects the respiratory and digestive systems. It evolves toward deterioration of pulmonary function through colonization with Pseudomonas aeruginosa. There is no consensus with respect to its eradication. Nebulized colistimethate is used for eradication treatment, b...

Full description

Bibliographic Details
Main Authors: Marie-Sophie Brochet, Anne-Catherine McDuff, Jean-François Bussières, Elaine Caron, Geneviève Fortin, Denis Lebel, Jacques-Édouard Marcotte
Format: Article
Language:English
Published: Hindawi Limited 2007-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/2007/673976
id doaj-10d793af074f426cb0792a9a26b100ad
record_format Article
spelling doaj-10d793af074f426cb0792a9a26b100ad2021-07-02T09:27:37ZengHindawi LimitedCanadian Respiratory Journal1198-22412007-01-0114847347910.1155/2007/673976Comparative Efficacy of Two Doses of Nebulized Colistimethate for the Eradication of Pseudomonas Aeruginosa in Children with Cystic FibrosisMarie-Sophie Brochet0Anne-Catherine McDuff1Jean-François Bussières2Elaine Caron3Geneviève Fortin4Denis Lebel5Jacques-Édouard Marcotte6Department of Pharmacy, CHU Sainte-Justine, Montreal, Quebec, CanadaDepartment of Pharmacy, CHU Sainte-Justine, Montreal, Quebec, CanadaDepartment of Pharmacy, CHU Sainte-Justine, Montreal, Quebec, CanadaDepartment of Pharmacy, CHU Sainte-Justine, Montreal, Quebec, CanadaDepartment of Pharmacy, CHU Sainte-Justine, Montreal, Quebec, CanadaDepartment of Pharmacy, CHU Sainte-Justine, Montreal, Quebec, CanadaDepartment of Pneumology, CHU Sainte-Justine, Montreal, Quebec, CanadaBACKGROUND: Cystic fibrosis (CF) affects the respiratory and digestive systems. It evolves toward deterioration of pulmonary function through colonization with Pseudomonas aeruginosa. There is no consensus with respect to its eradication. Nebulized colistimethate is used for eradication treatment, but the optimal dose and duration is yet to be determined.http://dx.doi.org/10.1155/2007/673976
collection DOAJ
language English
format Article
sources DOAJ
author Marie-Sophie Brochet
Anne-Catherine McDuff
Jean-François Bussières
Elaine Caron
Geneviève Fortin
Denis Lebel
Jacques-Édouard Marcotte
spellingShingle Marie-Sophie Brochet
Anne-Catherine McDuff
Jean-François Bussières
Elaine Caron
Geneviève Fortin
Denis Lebel
Jacques-Édouard Marcotte
Comparative Efficacy of Two Doses of Nebulized Colistimethate for the Eradication of Pseudomonas Aeruginosa in Children with Cystic Fibrosis
Canadian Respiratory Journal
author_facet Marie-Sophie Brochet
Anne-Catherine McDuff
Jean-François Bussières
Elaine Caron
Geneviève Fortin
Denis Lebel
Jacques-Édouard Marcotte
author_sort Marie-Sophie Brochet
title Comparative Efficacy of Two Doses of Nebulized Colistimethate for the Eradication of Pseudomonas Aeruginosa in Children with Cystic Fibrosis
title_short Comparative Efficacy of Two Doses of Nebulized Colistimethate for the Eradication of Pseudomonas Aeruginosa in Children with Cystic Fibrosis
title_full Comparative Efficacy of Two Doses of Nebulized Colistimethate for the Eradication of Pseudomonas Aeruginosa in Children with Cystic Fibrosis
title_fullStr Comparative Efficacy of Two Doses of Nebulized Colistimethate for the Eradication of Pseudomonas Aeruginosa in Children with Cystic Fibrosis
title_full_unstemmed Comparative Efficacy of Two Doses of Nebulized Colistimethate for the Eradication of Pseudomonas Aeruginosa in Children with Cystic Fibrosis
title_sort comparative efficacy of two doses of nebulized colistimethate for the eradication of pseudomonas aeruginosa in children with cystic fibrosis
publisher Hindawi Limited
series Canadian Respiratory Journal
issn 1198-2241
publishDate 2007-01-01
description BACKGROUND: Cystic fibrosis (CF) affects the respiratory and digestive systems. It evolves toward deterioration of pulmonary function through colonization with Pseudomonas aeruginosa. There is no consensus with respect to its eradication. Nebulized colistimethate is used for eradication treatment, but the optimal dose and duration is yet to be determined.
url http://dx.doi.org/10.1155/2007/673976
work_keys_str_mv AT mariesophiebrochet comparativeefficacyoftwodosesofnebulizedcolistimethatefortheeradicationofpseudomonasaeruginosainchildrenwithcysticfibrosis
AT annecatherinemcduff comparativeefficacyoftwodosesofnebulizedcolistimethatefortheeradicationofpseudomonasaeruginosainchildrenwithcysticfibrosis
AT jeanfrancoisbussieres comparativeefficacyoftwodosesofnebulizedcolistimethatefortheeradicationofpseudomonasaeruginosainchildrenwithcysticfibrosis
AT elainecaron comparativeefficacyoftwodosesofnebulizedcolistimethatefortheeradicationofpseudomonasaeruginosainchildrenwithcysticfibrosis
AT genevievefortin comparativeefficacyoftwodosesofnebulizedcolistimethatefortheeradicationofpseudomonasaeruginosainchildrenwithcysticfibrosis
AT denislebel comparativeefficacyoftwodosesofnebulizedcolistimethatefortheeradicationofpseudomonasaeruginosainchildrenwithcysticfibrosis
AT jacquesedouardmarcotte comparativeefficacyoftwodosesofnebulizedcolistimethatefortheeradicationofpseudomonasaeruginosainchildrenwithcysticfibrosis
_version_ 1721333048626118656