Network Pharmacology Analysis of the Identification of Phytochemicals and Therapeutic Mechanisms of Paeoniae Radix Alba for the Treatment of Asthma

Network Pharmacology Analysis of the Identification of Phytochemicals and Therapeutic Mechanisms of Paeoniae Radix Alba for the Treatment of Asthma

Background. Paeoniae Radix Alba (PRA), the root of the plant Paeonia lactiflora Pall., has been suggested to play an important role for the treatment of asthma. A biochemical understanding of the clinical effects of Paeoniae Radix Alba is needed. Here, we explore the phytochemicals and therapeutic m...

Full description

Bibliographic Details
Main Authors:	Jingwei Wang, Ling Peng, Lu Jin, Huiying Fu, Qiyang Shou
Format:	Article
Language:	English
Published:	Hindawi Limited 2021-01-01
Series:	Journal of Immunology Research
Online Access:	http://dx.doi.org/10.1155/2021/9659304

Similar Items

Efficacy, Chemical Constituents, and Pharmacological Actions of Radix Paeoniae Rubra and Radix Paeoniae Alba
by: Yu-Qing Tan, et al.
Published: (2020-07-01)

The Inhibition of Mast Cell Activation of Radix Paeoniae alba Extraction Identified by TCRP Based and Conventional Cell Function Assay Systems.
by: Huiying Fu, et al.
Published: (2016-01-01)

Paeoniae alba Radix Promotes Peripheral Nerve Regeneration
by: Kun-Shan Huang, et al.
Published: (2011-01-01)

The effects and mechanisms of Paeoniae alba Radix on nerve regeneration
by: Kun-Shan Huang, et al.
Published: (2009)

Effects of the different preparations of Paeoniae Alba Radix on the pharmacological effects of Shao-Yao-Kan-Tsao-Tang
by: Lin, Ying-Chih, et al.
Published: (1997)

Uncovering the mechanism of the effects of Paeoniae Radix Alba on iron-deficiency anaemia through a network pharmacology-based strategy
by: Xian-wen Ye, et al.
Published: (2020-04-01)

Carbon Dots from Paeoniae Radix Alba Carbonisata: Hepatoprotective Effect
by: Zhao Y, et al.
Published: (2020-11-01)

Mechanisms of P-Glycoprotein Modulation by Semen Strychni Combined with Radix Paeoniae Alba
by: Li-Li Liu, et al.
Published: (2017-01-01)

Identification of the tannins in traditional Chinese medicine Paeoniae Radix Alba by UHPLC-Q-Exactive Orbitrap MS
by: Pei Xiong, et al.
Published: (2021-11-01)

Studies on the Changes of Pharmacokinetics Behaviors of Phytochemicals and the Influence on Endogenous Metabolites After the Combination of Radix Bupleuri and Radix Paeoniae Alba Based on Multi-Component Pharmacokinetics and Metabolomics
by: Congcong Chen, et al.
Published: (2021-03-01)

Transcriptomics- and metabolomics-based integration analyses revealed the potential pharmacological effects and functional pattern of in vivo Radix Paeoniae Alba administration
by: Sining Wang, et al.
Published: (2020-05-01)

Single Standard Substance for the Simultaneous Determination of Eleven Components in the Extract of Paeoniae Radix Alba (Root of Paeonia lactiflora Pall.)
by: Menglan Shen, et al.
Published: (2021-01-01)

Phytochemical and pharmacological study on paeonia suffruticosa andrews
by: 陳慧懋
Published: (1991)

Mechanism of Paeoniae Radix Alba in the Treatment of Non-alcoholic Fatty Liver Disease Based on Sequential Metabolites Identification Approach, Network Pharmacology, and Binding Affinity Measurement
by: Zhiqiang Luo, et al.
Published: (2021-09-01)

Rapid monitoring the water extraction process of Radix Paeoniae Alba using near infrared spectroscopy
by: Tian Hu, et al.
Published: (2017-05-01)

HPLC-PDA combined with chemometrics for chemical markers of Paeoniae Radix Alba before and after sulfur-fumigated
by: Xiaozhou Jia, et al.
Published: (2021-01-01)

Investigation of Efficacy Enhancing and Toxicity Reducing Mechanism of Combination of Aconiti Lateralis Radix Praeparata and Paeoniae Radix Alba in Adjuvant-Induced Arthritis Rats by Metabolomics
by: Yun-fei Xie, et al.
Published: (2019-01-01)

Identification of metabolites of Radix Paeoniae Alba extract in rat bile, plasma and urine by ultra-performance liquid chromatographyâquadrupole time-of-flight mass spectrometry
by: Zheng-Wei Chen, et al.
Published: (2014-02-01)

Detection of Sulfur-Fumigated Paeoniae Alba Radix in Complex Preparations by High Performance Liquid Chromatography Tandem Mass Spectrometry
by: Song-Lin Li, et al.
Published: (2012-07-01)

Evaluation of the Influence of Sulfur-Fumigated Paeoniae Radix Alba on the Quality of Si Wu Tang by Chromatographic and Chemometric Analysis
by: Ke Pei, et al.
Published: (2016-01-01)

Antithrombotic Effect and Mechanism of Radix Paeoniae Rubra
by: Pingyao Xie, et al.
Published: (2017-01-01)

Effects of Paeoniae Radix on the Pharmacokinetics of Antiepileptic Agents
by: Lih-Chi Chen, et al.
Published: (2001)

Stability of paeoniflorin and paeonol from paeoniae radix
by: 洪千茵
Published: (2008)

Dissipation Behavior of Three Fungicides during the Industrial Processing of <i>Paeoniae</i> <i>Radix</i> Alba and Associated Processing Factors
by: Sheng-Nan Li, et al.
Published: (2019-06-01)

The Mechanism of the combination of radix paeoniae rubra-cortex moutan in treating cerebral hemorrhage based on network pharmacology
by: Jia-Qi Chen, et al.
Published: (2021-01-01)

The Correlation between Chemical Composition, as Determined by UPLC-TOF-MS, and Acute Toxicity of Veratrum nigrum L. and Radix paeoniae alba
by: Xianxie Zhang, et al.
Published: (2014-01-01)

Aqueous extract of Radix Paeoniae Alba and Gallic acid induce G2/M phase arrest and apoptosis in bladder carcinoma
by: Ting-Tsz, et al.
Published: (2010)

Radix Paeoniae Rubra and Radix Paeoniae Alba Attenuate CCl4-Induced Acute Liver Injury: An Ultra-Performance Liquid Chromatography-Mass Spectrometry (UPLC-MS) Based Metabolomic Approach for the Pharmacodynamic Study of Traditional Chinese Medicines (TCMs)
by: Qi-Wei Yang, et al.
Published: (2012-11-01)

Phytochemical Study on Paeonia suffruticosa Andrews
by: Shiou-Yu Ding, et al.
Published: (1994)

Anti-Inflammatory Effects, SAR, and Action Mechanism of Monoterpenoids from Radix Paeoniae Alba on LPS-Stimulated RAW 264.7 Cells
by: Xiaoxu Bi, et al.
Published: (2017-04-01)

Antihypertensive Effect of Radix Paeoniae Alba in Spontaneously Hypertensive Rats and Excessive Alcohol Intake and High Fat Diet Induced Hypertensive Rats
by: Chen Su-Hong, et al.
Published: (2015-01-01)

Integration of Metabolomics and Transcriptomics Reveals the Therapeutic Mechanism Underlying Paeoniflorin for the Treatment of Allergic Asthma
by: Qiyang Shou, et al.
Published: (2019-01-01)

Dertermination of Bioactive Components of Paeoniae Radix in Chinese Herbal Drugs
by: Yih-Joe Jan, et al.
Published: (1993)

Anti-Lung Cancer Targets of Radix Paeoniae Rubra and Biological Molecular Mechanism: Network Pharmacological Analyses and Experimental Validation
by: Ma Y, et al.
Published: (2021-03-01)

Study on Paeoniae Radix in Attenuating Hepatic Stellate Cell Activation and Migration
by: Chih-Yang Wang, et al.
Published: (2010)

Studies on the Active Components of Gardeniae Fructus, Paeoniae Radix, and Xanthii Fructus
by: 黃慕淇
Published: (1995)

To Probe Commercial Paeoniae Radix by using Chromatographic Similarity Analysis of HPLC
by: Ciou-Yi Lee, et al.
Published: (2005)

Removal of Matrix Interferences by Nano-MgO and Co-Adsorbents for Accurate Multi-Pesticide Residue Analysis in the Chinese Medicinal Herb, Paeoniae Radix Alba
by: Chunyu Wang, et al.
Published: (2021-01-01)

A Novel Method HPLC-DAD Analysis of the Contentsof Moutan Cortexand Paeoniae Radix Alba with Similar Constituents-Monoterpene Glycosides in Guizhi Fuling Wan
by: Shuyun Wang, et al.
Published: (2014-11-01)

Anti-Oxidant and Anti-Inflammatory Substance Generated Newly in Paeoniae Radix Alba Extract Fermented with Plant-Derived <i>Lactobacillus brevis</i> 174A
by: Shrijana Shakya, et al.
Published: (2021-07-01)