Safety and efficacy of the immunosuppressive agent 6-tioguanine in murine model of acute and chronic colitis

<p>Abstract</p> <p>Background</p> <p>Oral thiopurines are effective and widely used in treatment of inflammatory bowel disease (IBD) in humans, although their use is limited due the development of adverse events. Here, we examine the efficacy and toxicity of oral treatm...

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Main Authors: van Bodegraven Adriaan A, Vos Rene M, de Boer Nanne K, Jharap Bindia, Klimesova Klara, Tlaskalova-Hogenova Helena, Rossmann Pavel, Kverka Miloslav, Lukas Milan, Mulder Chris J
Format: Article
Language:English
Published: BMC 2011-05-01
Series:BMC Gastroenterology
Online Access:http://www.biomedcentral.com/1471-230X/11/47