Structural and functional evaluation of C. elegans filamins FLN-1 and FLN-2.

Filamins are long, flexible, multi-domain proteins composed of an N-terminal actin-binding domain (ABD) followed by multiple immunoglobulin-like repeats (IgFLN). They function to organize and maintain the actin cytoskeleton, to provide scaffolds for signaling components, and to act as mechanical for...

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Bibliographic Details
Main Authors: Christina R DeMaso, Ismar Kovacevic, Alper Uzun, Erin J Cram
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3143143?pdf=render