Length-dependent gene misexpression is associated with Alzheimer’s disease progression

Abstract Recent reports show transcription preference for long genes in neuronal tissues compared with non-neuronal tissues, and a gene-length dependent change in expression in the neurodevelopmental disease Rett syndrome (RTT). Whether the gene-length dependent changes in expression seen in RTT mig...

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Bibliographic Details
Main Authors: Shahar Barbash, Thomas P. Sakmar
Format: Article
Language:English
Published: Nature Publishing Group 2017-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-00250-4