An Acridine-Based Fluorescent Sensor for Monitoring ClO− in Water Samples and Zebrafish

A novel acridine-based fluorescent chemosensor, BK ((E)-2-((acridine-9-ylimino)methyl)-N-benzhydrylhydrazine-1-carbothioamide), for monitoring ClO− was prepared. The sensor BK was synthesized by introducing a new synthetic route of making...

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Main Authors:	Su Chan Lee, Soyoung Park, Haeri So, Gyudong Lee, Ki-Tae Kim, Cheal Kim
Format:	Article
Language:	English
Published:	MDPI AG 2020-08-01
Series:	Sensors
Subjects:	acridine fluorescent chemosensor hypochlorite zebrafish theoretical calculations
Online Access:	https://www.mdpi.com/1424-8220/20/17/4764

id	doaj-10c06b45d132477a87b0a73b9d33245a
record_format	Article
spelling	doaj-10c06b45d132477a87b0a73b9d33245a2020-11-25T02:58:47ZengMDPI AGSensors1424-82202020-08-01204764476410.3390/s20174764An Acridine-Based Fluorescent Sensor for Monitoring ClO<sup>−</sup> in Water Samples and ZebrafishSu Chan Lee0Soyoung Park1Haeri So2Gyudong Lee3Ki-Tae Kim4Cheal Kim5Department of Fine Chemistry, Seoul National University of Science and Technology, Seoul 136-741, KoreaDepartment of Fine Chemistry, Seoul National University of Science and Technology, Seoul 136-741, KoreaDepartment of Fine Chemistry, Seoul National University of Science and Technology, Seoul 136-741, KoreaDepartment of Environmental Engineering, Seoul National University of Science and Technology, Seoul 136-741, KoreaDepartment of Environmental Engineering, Seoul National University of Science and Technology, Seoul 136-741, KoreaDepartment of Fine Chemistry, Seoul National University of Science and Technology, Seoul 136-741, KoreaA novel acridine-based fluorescent chemosensor, <b>BK</b> ((E)-2-((acridine-9-ylimino)methyl)-N-benzhydrylhydrazine-1-carbothioamide), for monitoring ClO<sup>−</sup> was prepared. The sensor <b>BK</b> was synthesized by introducing a new synthetic route of making aldehyde group using formic hydrazide. Probe <b>BK</b> displayed notable fluorescence quenching in the presence of ClO<sup>−</sup> and showed a great selectivity over other guest analytes. The detection limit was calculated to be 7.65 μM. Additionally, <b>BK</b> was satisfactorily applied for sensing ClO<sup>−</sup> in water samples and zebrafish.https://www.mdpi.com/1424-8220/20/17/4764acridinefluorescent chemosensorhypochloritezebrafishtheoretical calculations
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Su Chan Lee Soyoung Park Haeri So Gyudong Lee Ki-Tae Kim Cheal Kim
spellingShingle	Su Chan Lee Soyoung Park Haeri So Gyudong Lee Ki-Tae Kim Cheal Kim An Acridine-Based Fluorescent Sensor for Monitoring ClO<sup>−</sup> in Water Samples and Zebrafish Sensors acridine fluorescent chemosensor hypochlorite zebrafish theoretical calculations
author_facet	Su Chan Lee Soyoung Park Haeri So Gyudong Lee Ki-Tae Kim Cheal Kim
author_sort	Su Chan Lee
title	An Acridine-Based Fluorescent Sensor for Monitoring ClO<sup>−</sup> in Water Samples and Zebrafish
title_short	An Acridine-Based Fluorescent Sensor for Monitoring ClO<sup>−</sup> in Water Samples and Zebrafish
title_full	An Acridine-Based Fluorescent Sensor for Monitoring ClO<sup>−</sup> in Water Samples and Zebrafish
title_fullStr	An Acridine-Based Fluorescent Sensor for Monitoring ClO<sup>−</sup> in Water Samples and Zebrafish
title_full_unstemmed	An Acridine-Based Fluorescent Sensor for Monitoring ClO<sup>−</sup> in Water Samples and Zebrafish
title_sort	acridine-based fluorescent sensor for monitoring clo<sup>−</sup> in water samples and zebrafish
publisher	MDPI AG
series	Sensors
issn	1424-8220
publishDate	2020-08-01
description	A novel acridine-based fluorescent chemosensor, <b>BK</b> ((E)-2-((acridine-9-ylimino)methyl)-N-benzhydrylhydrazine-1-carbothioamide), for monitoring ClO<sup>−</sup> was prepared. The sensor <b>BK</b> was synthesized by introducing a new synthetic route of making aldehyde group using formic hydrazide. Probe <b>BK</b> displayed notable fluorescence quenching in the presence of ClO<sup>−</sup> and showed a great selectivity over other guest analytes. The detection limit was calculated to be 7.65 μM. Additionally, <b>BK</b> was satisfactorily applied for sensing ClO<sup>−</sup> in water samples and zebrafish.
topic	acridine fluorescent chemosensor hypochlorite zebrafish theoretical calculations
url	https://www.mdpi.com/1424-8220/20/17/4764
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An Acridine-Based Fluorescent Sensor for Monitoring ClO<sup>−</sup> in Water Samples and Zebrafish

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