Exploration of the Prognostic and Immunotherapeutic Value of B and T Lymphocyte Attenuator in Skin Cutaneous Melanoma

Exploration of the Prognostic and Immunotherapeutic Value of B and T Lymphocyte Attenuator in Skin Cutaneous Melanoma

B and T lymphocyte attenuator (BTLA) is a newly identified immune checkpoint molecular belonging to the CD28 immunoglobulin superfamily. However, the expression and clinical value of BTLA in skin cutaneous melanoma (SKCM) has not been widely characterized. We found that BTLA levels were upregulated...

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Bibliographic Details
Main Authors: Xubin Dong, Jingjing Song, Buran Chen, Yufeng Qi, Wenjie Jiang, Huihui Li, Danni Zheng, Yinghao Wang, Xiaohua Zhang, Haiguang Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Oncology
Subjects:
B and T lymphocyte attenuator (BTLA)
skin cutaneous melanoma
tumor-infiltration
tumor microenvironment
prognosis
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.592811/full

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https://www.frontiersin.org/articles/10.3389/fonc.2020.592811/full

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