Dietary agent, benzyl isothiocyanate inhibits signal transducer and activator of transcription 3 phosphorylation and collaborates with sulforaphane in the growth suppression of PANC-1 cancer cells

<p>Abstract</p> <p>The Signal Transducer and Activator of Transcription (STAT) proteins comprise a family of latent transcription factors with diverse functions. STAT3 has well established roles in cell proliferation, growth and survival, and its persistent activation has been dete...

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Bibliographic Details
Main Authors: Deangelis Stephanie, Cen Ling, Jones Sarah, Willis William, Hutzen Brian, Fuh Beng, Lin Jiayuh
Format: Article
Language:English
Published: BMC 2009-08-01
Series:Cancer Cell International
Online Access:http://www.cancerci.com/content/9/1/24