SPONTANEOUS IMMUNOGLOBULIN-SYNTHESIZING ACTIVITY OF B LYMPHOCYTES IN INFLAMMATORY RHEUMATIC DISEASES

Abstract. The aim of present work was to evaluate clinical significance of B-lymphocytes spontaneous antibody-synthesizing activity by B-lymphocytes (LASA) in patients with rheumatic inflammatory diseases (RD), i.e., reactive arthritis (ReA), ankylosing spondylitis (AS), rheumatoid arthritis (RA), a...

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Main Authors: A.T. T. Mamasaidov, K. T. Ashirov, G. M. Mamasaidova, G. A. Kulchinova, D. I. Abdurashitova, M. Yu. Shakirov, A. P. Irissov, Ch. A. Eshbaeva, Z. B. Nurmamatov
Format: Article
Language:Russian
Published: SPb RAACI 2014-07-01
Series:Medicinskaâ Immunologiâ
Subjects:
Online Access:https://www.mimmun.ru/mimmun/article/view/235
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spelling doaj-10a0303c4c7c4a5abd53ee57ccb2d2012021-07-29T09:02:23ZrusSPb RAACIMedicinskaâ Immunologiâ1563-06252313-741X2014-07-0194-552753010.15789/1563-0625-2007-4-5-527-530232SPONTANEOUS IMMUNOGLOBULIN-SYNTHESIZING ACTIVITY OF B LYMPHOCYTES IN INFLAMMATORY RHEUMATIC DISEASESA.T. T. Mamasaidov0K. T. Ashirov1G. M. Mamasaidova2G. A. Kulchinova3D. I. Abdurashitova4M. Yu. Shakirov5A. P. Irissov6Ch. A. Eshbaeva7Z. B. Nurmamatov8Центр последипломного медицинского образования, г. ОшОшский государственный университет, г. Бишкек и г. ОшКыргызская государственная медицинская академияКыргызская государственная медицинская академияОшский государственный университет, г. Бишкек и г. ОшЦентр последипломного медицинского образования, г. ОшОшский государственный университет, г. Бишкек и г. ОшЦентр последипломного медицинского образования, г. ОшЦентр последипломного медицинского образования, г. ОшAbstract. The aim of present work was to evaluate clinical significance of B-lymphocytes spontaneous antibody-synthesizing activity by B-lymphocytes (LASA) in patients with rheumatic inflammatory diseases (RD), i.e., reactive arthritis (ReA), ankylosing spondylitis (AS), rheumatoid arthritis (RA), and systemic lupus erythematosus (SLE). Significantly higher LASA levels were revealed in the patients with ReA, AS, RA, and SLE, as compared with healthy persons and patients with osteoarthrosis. Clinical significance of LASA indexes and their changes may reflect manifestation and degree of immunological activities in ReA, AS, RA, and SLE.https://www.mimmun.ru/mimmun/article/view/235reactive arthritisankylosing spondylitisrheumatoid arthritissystemic lupus erythematosusrheumatic inflammatory diseasesв-lymphocytesimmunoglobulins
collection DOAJ
language Russian
format Article
sources DOAJ
author A.T. T. Mamasaidov
K. T. Ashirov
G. M. Mamasaidova
G. A. Kulchinova
D. I. Abdurashitova
M. Yu. Shakirov
A. P. Irissov
Ch. A. Eshbaeva
Z. B. Nurmamatov
spellingShingle A.T. T. Mamasaidov
K. T. Ashirov
G. M. Mamasaidova
G. A. Kulchinova
D. I. Abdurashitova
M. Yu. Shakirov
A. P. Irissov
Ch. A. Eshbaeva
Z. B. Nurmamatov
SPONTANEOUS IMMUNOGLOBULIN-SYNTHESIZING ACTIVITY OF B LYMPHOCYTES IN INFLAMMATORY RHEUMATIC DISEASES
Medicinskaâ Immunologiâ
reactive arthritis
ankylosing spondylitis
rheumatoid arthritis
systemic lupus erythematosus
rheumatic inflammatory diseases
в-lymphocytes
immunoglobulins
author_facet A.T. T. Mamasaidov
K. T. Ashirov
G. M. Mamasaidova
G. A. Kulchinova
D. I. Abdurashitova
M. Yu. Shakirov
A. P. Irissov
Ch. A. Eshbaeva
Z. B. Nurmamatov
author_sort A.T. T. Mamasaidov
title SPONTANEOUS IMMUNOGLOBULIN-SYNTHESIZING ACTIVITY OF B LYMPHOCYTES IN INFLAMMATORY RHEUMATIC DISEASES
title_short SPONTANEOUS IMMUNOGLOBULIN-SYNTHESIZING ACTIVITY OF B LYMPHOCYTES IN INFLAMMATORY RHEUMATIC DISEASES
title_full SPONTANEOUS IMMUNOGLOBULIN-SYNTHESIZING ACTIVITY OF B LYMPHOCYTES IN INFLAMMATORY RHEUMATIC DISEASES
title_fullStr SPONTANEOUS IMMUNOGLOBULIN-SYNTHESIZING ACTIVITY OF B LYMPHOCYTES IN INFLAMMATORY RHEUMATIC DISEASES
title_full_unstemmed SPONTANEOUS IMMUNOGLOBULIN-SYNTHESIZING ACTIVITY OF B LYMPHOCYTES IN INFLAMMATORY RHEUMATIC DISEASES
title_sort spontaneous immunoglobulin-synthesizing activity of b lymphocytes in inflammatory rheumatic diseases
publisher SPb RAACI
series Medicinskaâ Immunologiâ
issn 1563-0625
2313-741X
publishDate 2014-07-01
description Abstract. The aim of present work was to evaluate clinical significance of B-lymphocytes spontaneous antibody-synthesizing activity by B-lymphocytes (LASA) in patients with rheumatic inflammatory diseases (RD), i.e., reactive arthritis (ReA), ankylosing spondylitis (AS), rheumatoid arthritis (RA), and systemic lupus erythematosus (SLE). Significantly higher LASA levels were revealed in the patients with ReA, AS, RA, and SLE, as compared with healthy persons and patients with osteoarthrosis. Clinical significance of LASA indexes and their changes may reflect manifestation and degree of immunological activities in ReA, AS, RA, and SLE.
topic reactive arthritis
ankylosing spondylitis
rheumatoid arthritis
systemic lupus erythematosus
rheumatic inflammatory diseases
в-lymphocytes
immunoglobulins
url https://www.mimmun.ru/mimmun/article/view/235
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