Considerations for Treating Corona Virus (Sars-Cov-2) Infection with Passive Immunotherapy

The corona viruses are transient RNA viruses; once an infected individual recovers he or she becomes virus-free and immune. One could expect that in SARS-Covid-19 also, infected individuals who recover will have developed some form of protective immunity. Very little is yet known about its developm...

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Main Authors: Abraham Karpas, Douglas Bainbridge, Stephen Ash
Format: Article
Language:English
Published: Firenze University Press 2020-05-01
Series:Substantia
Subjects:
Online Access:https://riviste.fupress.net/index.php/subs/article/view/924
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spelling doaj-108a69c48b7c40bab6108708f75b55a22020-11-25T02:53:55ZengFirenze University PressSubstantia2532-39972020-05-014110.13128/Substantia-924Considerations for Treating Corona Virus (Sars-Cov-2) Infection with Passive ImmunotherapyAbraham Karpas0Douglas Bainbridge1Stephen Ash2formerly Assistant Director of Research, Department of Haematology, Cambridge University Clinical School, UKEmeritus Consultant in Immunology, Royal London HospitalAssociate Dean and Emeritus Professor of Infectious Diseases, AUC School of Medicine, UK The corona viruses are transient RNA viruses; once an infected individual recovers he or she becomes virus-free and immune. One could expect that in SARS-Covid-19 also, infected individuals who recover will have developed some form of protective immunity. Very little is yet known about its development, when and for how long it might last, and though it is very likely to involve virus-neutralising antibodies, to what extent it might depend on the appearance of such antibodies. However in a recent report 10 very advanced corona patients were treated with a single 200 ml dose of plasma obtained from individuals recovered from the infection. There was impressive clinical improvement. https://riviste.fupress.net/index.php/subs/article/view/924CoronavirusSars-cov-2covid-19immunotherapyemergency
collection DOAJ
language English
format Article
sources DOAJ
author Abraham Karpas
Douglas Bainbridge
Stephen Ash
spellingShingle Abraham Karpas
Douglas Bainbridge
Stephen Ash
Considerations for Treating Corona Virus (Sars-Cov-2) Infection with Passive Immunotherapy
Substantia
Coronavirus
Sars-cov-2
covid-19
immunotherapy
emergency
author_facet Abraham Karpas
Douglas Bainbridge
Stephen Ash
author_sort Abraham Karpas
title Considerations for Treating Corona Virus (Sars-Cov-2) Infection with Passive Immunotherapy
title_short Considerations for Treating Corona Virus (Sars-Cov-2) Infection with Passive Immunotherapy
title_full Considerations for Treating Corona Virus (Sars-Cov-2) Infection with Passive Immunotherapy
title_fullStr Considerations for Treating Corona Virus (Sars-Cov-2) Infection with Passive Immunotherapy
title_full_unstemmed Considerations for Treating Corona Virus (Sars-Cov-2) Infection with Passive Immunotherapy
title_sort considerations for treating corona virus (sars-cov-2) infection with passive immunotherapy
publisher Firenze University Press
series Substantia
issn 2532-3997
publishDate 2020-05-01
description The corona viruses are transient RNA viruses; once an infected individual recovers he or she becomes virus-free and immune. One could expect that in SARS-Covid-19 also, infected individuals who recover will have developed some form of protective immunity. Very little is yet known about its development, when and for how long it might last, and though it is very likely to involve virus-neutralising antibodies, to what extent it might depend on the appearance of such antibodies. However in a recent report 10 very advanced corona patients were treated with a single 200 ml dose of plasma obtained from individuals recovered from the infection. There was impressive clinical improvement.
topic Coronavirus
Sars-cov-2
covid-19
immunotherapy
emergency
url https://riviste.fupress.net/index.php/subs/article/view/924
work_keys_str_mv AT abrahamkarpas considerationsfortreatingcoronavirussarscov2infectionwithpassiveimmunotherapy
AT douglasbainbridge considerationsfortreatingcoronavirussarscov2infectionwithpassiveimmunotherapy
AT stephenash considerationsfortreatingcoronavirussarscov2infectionwithpassiveimmunotherapy
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