Regulation of the Human Papillomavirus Lifecyle through Post-Translational Modifications of the Viral E2 Protein

Regulation of the Human Papillomavirus Lifecyle through Post-Translational Modifications of the Viral E2 Protein

The human papillomavirus (HPV) is a DNA tumor virus that infects cutaneous and mucosal epithelia where high-risk (HR) HPV infections lead to cervical, oropharyngeal, and anogenital cancers. Worldwide, nearly 5% of all cancers are caused by HR HPV. The viral E2 protein is essential for episomal repli...

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Bibliographic Details
Main Authors: Leny Jose, Timra Gilson, Elliot J. Androphy, Marsha DeSmet
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Pathogens
Subjects:
HPV E2
replication
PTM
Online Access:https://www.mdpi.com/2076-0817/10/7/793

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