Contribution of Post-translational Phosphorylation to Sarcomere-linked Cardiomyopathy Phenotypes

Contribution of Post-translational Phosphorylation to Sarcomere-linked Cardiomyopathy Phenotypes

Secondary shifts develop in post-translational phosphorylation of sarcomeric proteins in multi¬ple animal models of inherited cardiomyopathy. These signaling alterations together with the primary mutation are predicted to contribute to the overall cardiac phenotype. As a result, identification and...

Full description

Bibliographic Details
Main Author: Margaret V Westfall
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Physiology
Subjects:
Phosphorylation
signaling
cardiomyopathy
post-translational modification
Myofilament
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00407/full

Similar Items

Similar Items