Oral Supplementation Effect of Iron and its Complex Form With Quercetin on Oxidant Status and on Redistribution of Essential Metals in Organs of Streptozotocin Diabetic Rats
Background and aims: Quercetin, is a polyphenolic antioxidant compound. It is able to form complex with metal ions such as iron and exerts a broad range of biological activities like improving metabolic disorders. This research aims at investigating the effect of oral supplementation of iron (2.5mg...
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2019-03-01
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| Series: | Romanian Journal of Diabetes Nutrition and Metabolic Diseases |
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| Online Access: | https://doi.org/10.2478/rjdnmd-2019-0005 |
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doaj-107782852b9747b59d2ef9da0bff9e1a2021-09-05T14:01:24ZengSciendoRomanian Journal of Diabetes Nutrition and Metabolic Diseases2284-64172019-03-01261395310.2478/rjdnmd-2019-0005rjdnmd-2019-0005Oral Supplementation Effect of Iron and its Complex Form With Quercetin on Oxidant Status and on Redistribution of Essential Metals in Organs of Streptozotocin Diabetic RatsBerroukeche Farid0Mokhtari-Soulimane Nassima1Imessaoudene Asmahan2Cherrak Ahmed Sabri3Ronot Pascale4Boos Anne5Belhandouz Amina6Merzouk Hafida7Elhabiri Mourad8Laboratory of Physiology, Pathophysiology and Biochemistry of Nutrition Department of Biology, Faculty of Natural and Life Sciences, Earth and Universe, Tlemcen University, AlgeriaLaboratory of Physiology, Pathophysiology and Biochemistry of Nutrition Department of Biology, Faculty of Natural and Life Sciences, Earth and Universe, Tlemcen University, AlgeriaLaboratory of Physiology, Pathophysiology and Biochemistry of Nutrition Department of Biology, Faculty of Natural and Life Sciences, Earth and Universe, Tlemcen University, AlgeriaLaboratory of Physiology, Pathophysiology and Biochemistry of Nutrition Department of Biology, Faculty of Natural and Life Sciences, Earth and Universe, Tlemcen University, AlgeriaIPHC, Becquerel Street, Strasbourg University, FranceIPHC, Becquerel Street, Strasbourg University, FranceFaculty of Medecine, Bechar University, AlgeriaLaboratory of Physiology, Pathophysiology and Biochemistry of Nutrition Department of Biology, Faculty of Natural and Life Sciences, Earth and Universe, Tlemcen University, AlgeriaLaboratory of Physico-Chemistry Bioinorganic, UMR 7509 of CNRS, ECPM, Louis Pasteur University, 25 Becquerel street, Bat R5-Level 1, 67200Strasbourg, FranceBackground and aims: Quercetin, is a polyphenolic antioxidant compound. It is able to form complex with metal ions such as iron and exerts a broad range of biological activities like improving metabolic disorders. This research aims at investigating the effect of oral supplementation of iron (2.5mg Fe/Kg/day) and its complex form (molar ratio 1:5; 2.5mg/25mg/Kg/day) with quercetin (25mg/Kg/day) on lipid metabolism, oxidant status and trace elements contents in organs of Wistar diabetic rats (45 mg/kg/rat.ip of streptozotocin) during eight weeks of experimentation.https://doi.org/10.2478/rjdnmd-2019-0005iron-quercetin complexdiabetesoxidative stresslipoproteinstrace elements |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Berroukeche Farid Mokhtari-Soulimane Nassima Imessaoudene Asmahan Cherrak Ahmed Sabri Ronot Pascale Boos Anne Belhandouz Amina Merzouk Hafida Elhabiri Mourad |
| spellingShingle |
Berroukeche Farid Mokhtari-Soulimane Nassima Imessaoudene Asmahan Cherrak Ahmed Sabri Ronot Pascale Boos Anne Belhandouz Amina Merzouk Hafida Elhabiri Mourad Oral Supplementation Effect of Iron and its Complex Form With Quercetin on Oxidant Status and on Redistribution of Essential Metals in Organs of Streptozotocin Diabetic Rats Romanian Journal of Diabetes Nutrition and Metabolic Diseases iron-quercetin complex diabetes oxidative stress lipoproteins trace elements |
| author_facet |
Berroukeche Farid Mokhtari-Soulimane Nassima Imessaoudene Asmahan Cherrak Ahmed Sabri Ronot Pascale Boos Anne Belhandouz Amina Merzouk Hafida Elhabiri Mourad |
| author_sort |
Berroukeche Farid |
| title |
Oral Supplementation Effect of Iron and its Complex Form With Quercetin on Oxidant Status and on Redistribution of Essential Metals in Organs of Streptozotocin Diabetic Rats |
| title_short |
Oral Supplementation Effect of Iron and its Complex Form With Quercetin on Oxidant Status and on Redistribution of Essential Metals in Organs of Streptozotocin Diabetic Rats |
| title_full |
Oral Supplementation Effect of Iron and its Complex Form With Quercetin on Oxidant Status and on Redistribution of Essential Metals in Organs of Streptozotocin Diabetic Rats |
| title_fullStr |
Oral Supplementation Effect of Iron and its Complex Form With Quercetin on Oxidant Status and on Redistribution of Essential Metals in Organs of Streptozotocin Diabetic Rats |
| title_full_unstemmed |
Oral Supplementation Effect of Iron and its Complex Form With Quercetin on Oxidant Status and on Redistribution of Essential Metals in Organs of Streptozotocin Diabetic Rats |
| title_sort |
oral supplementation effect of iron and its complex form with quercetin on oxidant status and on redistribution of essential metals in organs of streptozotocin diabetic rats |
| publisher |
Sciendo |
| series |
Romanian Journal of Diabetes Nutrition and Metabolic Diseases |
| issn |
2284-6417 |
| publishDate |
2019-03-01 |
| description |
Background and aims: Quercetin, is a polyphenolic antioxidant compound. It is able to form complex with metal ions such as iron and exerts a broad range of biological activities like improving metabolic disorders. This research aims at investigating the effect of oral supplementation of iron (2.5mg Fe/Kg/day) and its complex form (molar ratio 1:5; 2.5mg/25mg/Kg/day) with quercetin (25mg/Kg/day) on lipid metabolism, oxidant status and trace elements contents in organs of Wistar diabetic rats (45 mg/kg/rat.ip of streptozotocin) during eight weeks of experimentation. |
| topic |
iron-quercetin complex diabetes oxidative stress lipoproteins trace elements |
| url |
https://doi.org/10.2478/rjdnmd-2019-0005 |
| work_keys_str_mv |
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