GTL-1, a Calcium Activated TRPM Channel, Enhances Nociception

GTL-1, a Calcium Activated TRPM Channel, Enhances Nociception

C. elegans PVD neurons are conserved for morphology, function and molecular determinants with mammalian polymodal nociceptors. Functions of polymodal nociceptors require activities of multiple ion channels and receptors including members of the TRP family. GTL-1, a member of the TRPM subclass of TRP...

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Bibliographic Details
Main Authors: Emiliano Cohen, Rakesh Kumar, Tal Zinger, Avi Priel, Millet Treinin
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Pharmacology
Subjects:
TRPM
C. elegans
nociceptors
calcium
behavior
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01567/full

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