Computational pan-genome mapping and pairwise SNP-distance improve detection of Mycobacterium tuberculosis transmission clusters.

Computational pan-genome mapping and pairwise SNP-distance improve detection of Mycobacterium tuberculosis transmission clusters.

Next-generation sequencing based base-by-base distance measures have become an integral complement to epidemiological investigation of infectious disease outbreaks. This study introduces PANPASCO, a computational pan-genome mapping based, pairwise distance method that is highly sensitive to differen...

Full description

Bibliographic Details
Main Authors: Christine Jandrasits, Stefan Kröger, Walter Haas, Bernhard Y Renard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-12-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007527

Similar Items

Similar Items