Central diabetes insipidus unmasked by corticosteroid therapy for cerebral metastases: beware the case with pituitary involvement and hypopituitarism

Central diabetes insipidus unmasked by corticosteroid therapy for cerebral metastases: beware the case with pituitary involvement and hypopituitarism

Patients with intra-cerebral metastases often receive glucocorticoids, particularly in the presence of peri-lesional vasogenic cerebral oedema. We present a case of presumptive lung carcinoma with cerebral metastases where central diabetes insipidus was unmasked after glucocorticoid administration a...

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Bibliographic Details
Main Authors: HX Chin, TPL Quek, MKS Leow
Format: Article
Language:English
Published: Royal College of Physicians of Edinburgh 2017-09-01
Series:The Journal of the Royal College of Physicians of Edinburgh
Subjects:
anti-diuretic hormone
arginine vasopressin
central diabetes insipidus
cerebral metastases
glucocorticoids
pituitary
Online Access:https://www.rcpe.ac.uk/sites/default/files/jrcpe_47_3_chin.pdf
Description
Summary:Patients with intra-cerebral metastases often receive glucocorticoids, particularly in the presence of peri-lesional vasogenic cerebral oedema. We present a case of presumptive lung carcinoma with cerebral metastases where central diabetes insipidus was unmasked after glucocorticoid administration and correction of undiagnosed central hypocortisolism.
ISSN:1478-2715
2042-8189

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