Shared Neurodevelopmental Perturbations Can Lead to Intellectual Disability in Individuals with Distinct Rare Chromosome Duplications

Shared Neurodevelopmental Perturbations Can Lead to Intellectual Disability in Individuals with Distinct Rare Chromosome Duplications

Chromosomal duplications are associated with a large group of human diseases that arise mainly from dosage imbalance of genes within the rearrangements. Phenotypes range widely but are often associated with global development delay, intellectual disability, autism spectrum disorders, and multiple co...

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Bibliographic Details
Main Authors: Thiago Corrêa, Cíntia B. Santos-Rebouças, Maytza Mayndra, Albert Schinzel, Mariluce Riegel
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Genes
Subjects:
duplication syndromes
intellectual disability
axon guidance
PPI-network
Online Access:https://www.mdpi.com/2073-4425/12/5/632

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