An introduction to the science of epigenetics
<p>Epigenetics has emerged as an important new discipline. This review provides deeper insights into understanding basic defects in methylation, histone modification, and RNA induced silencing of tumours. These mechanisms have important diagnostic and therapeutic implications for many tumours...
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Association of Clinical Pathologists of Nepal
2013-03-01
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| Series: | Journal of Pathology of Nepal |
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| Online Access: | http://www.nepjol.info/index.php/JPN/article/view/7870 |
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doaj-1055a064dc0349649149ec999845d7cd2020-11-24T21:36:17ZengAssociation of Clinical Pathologists of NepalJournal of Pathology of Nepal2091-07972091-09082013-03-013540841010.3126/jpn.v3i5.78706337An introduction to the science of epigeneticsJB Thapa0Pathology Department, Himal Hospital Pvt. Ltd., Kathmandu,<p>Epigenetics has emerged as an important new discipline. This review provides deeper insights into understanding basic defects in methylation, histone modification, and RNA induced silencing of tumours. These mechanisms have important diagnostic and therapeutic implications for many tumours and diseases. New anti-epigenetic based drug therapies have been developed and drug trials are underway. The future will see further developments in this field.</p> <p>Journal of Pathology of Nepal (2013) Vol. 3, No.1, Issue 5, 408-410</p> <p>DOI: <a href="http://dx.doi.org/10.3126/jpn.v3i5.7870">http://dx.doi.org/10.3126/jpn.v3i5.7870</a></p>http://www.nepjol.info/index.php/JPN/article/view/7870EpigeneticsHistone modificationRNATumour methylation |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
JB Thapa |
| spellingShingle |
JB Thapa An introduction to the science of epigenetics Journal of Pathology of Nepal Epigenetics Histone modification RNA Tumour methylation |
| author_facet |
JB Thapa |
| author_sort |
JB Thapa |
| title |
An introduction to the science of epigenetics |
| title_short |
An introduction to the science of epigenetics |
| title_full |
An introduction to the science of epigenetics |
| title_fullStr |
An introduction to the science of epigenetics |
| title_full_unstemmed |
An introduction to the science of epigenetics |
| title_sort |
introduction to the science of epigenetics |
| publisher |
Association of Clinical Pathologists of Nepal |
| series |
Journal of Pathology of Nepal |
| issn |
2091-0797 2091-0908 |
| publishDate |
2013-03-01 |
| description |
<p>Epigenetics has emerged as an important new discipline. This review provides deeper insights into understanding basic defects in methylation, histone modification, and RNA induced silencing of tumours. These mechanisms have important diagnostic and therapeutic implications for many tumours and diseases. New anti-epigenetic based drug therapies have been developed and drug trials are underway. The future will see further developments in this field.</p> <p>Journal of Pathology of Nepal (2013) Vol. 3, No.1, Issue 5, 408-410</p> <p>DOI: <a href="http://dx.doi.org/10.3126/jpn.v3i5.7870">http://dx.doi.org/10.3126/jpn.v3i5.7870</a></p> |
| topic |
Epigenetics Histone modification RNA Tumour methylation |
| url |
http://www.nepjol.info/index.php/JPN/article/view/7870 |
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AT jbthapa anintroductiontothescienceofepigenetics AT jbthapa introductiontothescienceofepigenetics |
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