Correlation of Serum Zinc Level with Simple Febrile Seizures: A Hospital based Prospective Case Control Study

• Main Authors: Imran Gattoo, Rekha Harish, Sheikh Quyoom Hussain
• Format: Article
• Language: English
• Published: Mashhad University of Medical Sciences 2015-04-01
• Series: International Journal of Pediatrics
• Subjects: Simple Febrile seizures; serum zinc levels; children; convulsions and epilepsy
• Online Access: http://ijp.mums.ac.ir/pdf_4109_536afcbb1a728d974959225a1ad4672e.html

Background: Febrile seizures are one of the most common neurological conditions of childhood. It seems that zinc deficiency is associated with increased risk of febrile seizures.Aim: To estimate the serum Zinc level in children with simple Febrile seizures and to find the correlation between serum zinc level and simple Febrile seizures.Materials and Methods: The proposed study was a hospital based prospective case control study which included infants and children aged between 6 months to 5 years, at Post Graduate Department of Pediatrics, (SMGS) Hospital, GMC Jammu, northern India. A total of 200 infants and children fulfilling the inclusion criteria were included. Patients were divided into 100(cases) in Group A with simple febrile seizure and 100(controls) in Group B of children with acute febrile illness without seizure. All patients were subjected to detailed history and thorough clinical examination followed by relevant investigations.Results: Our study had slight male prepondance of 62% in cases and 58% in controls . Mean serum zinc level in cases was 61.53±15.87 ugm/dl and in controls it was 71.90+18.50 ugm/dl .Serum zinc level was found significantly low in cases of simple febrile seizures as compaired to controls ,with p value of