The Effect of Granisetron on Sensory Detection and Pain Thresholds in Facial Skin of Healthy Young Males

The Effect of Granisetron on Sensory Detection and Pain Thresholds in Facial Skin of Healthy Young Males

Background: The specific serotonin type 3 (5-HT3)-receptor antagonist granisetron effectively reduces clinical as well as experimental muscle pain and hyperalgesia and with a duration that exceeds that of lidocaine. Hence, it may be an alternative to lidocaine as a local anesthetic. There are also s...

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Bibliographic Details
Main Authors: Malin Ernberg, Anna Wieslander Fältmars, Milad Hajizadeh Kopayeh, Sofia Arzt Wallén, Therese Cankalp, Nikolaos Christidis
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Neurology
Subjects:
granisetron
sodium channels
lidocaine
human
mechanical thresholds
thermal thresholds
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.00237/full

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