Recovery of a triazole-resistant Aspergillus fumigatus in respiratory specimen of COVID-19 patient in ICU – A case report

Recovery of a triazole-resistant Aspergillus fumigatus in respiratory specimen of COVID-19 patient in ICU – A case report

Although invasive pulmonary aspergillosis (IPA) is typically described in immunocompromised host, patient with severe influenzae can develop IPA. Similarly, patients with severe COVID-19 complicated with IPA are increasingly reported. Here, we describe a case of invasive aspergillosis with triazole-...

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Bibliographic Details
Main Authors: Théo Ghelfenstein-Ferreira, Anastasia Saade, Alexandre Alanio, Stéphane Bretagne, Raffael Araujo de Castro, Samia Hamane, Elie Azoulay, Swann Bredin, Sarah Dellière
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Medical Mycology Case Reports
Subjects:
Aspergillosis
COVID-19
ICU
Triazole-resistance
Coronavirus
SARS-CoV2
Online Access:http://www.sciencedirect.com/science/article/pii/S2211753920300439
Description
Summary:Although invasive pulmonary aspergillosis (IPA) is typically described in immunocompromised host, patient with severe influenzae can develop IPA. Similarly, patients with severe COVID-19 complicated with IPA are increasingly reported. Here, we describe a case of invasive aspergillosis with triazole-resistant A. fumigatus (TR34/L98H mutation) in a 56-year-old patient with COVID-19 in intensive care unit. This report highlights the need to define the available tools for diagnosis of invasive aspergillosis in severe COVID-19 patients.
ISSN:2211-7539

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