Transient neuromyopathy after bromide intoxication in a dog with idiopathic epilepsy

Transient neuromyopathy after bromide intoxication in a dog with idiopathic epilepsy

<p>Abstract</p> <p>A seven-year old Australian Shepherd, suffering from idiopathic epilepsy under treatment with phenobarbitone and potassium bromide, was presented with generalised lower motor neuron signs. Electrophysiology and muscle-nerve biopsies revealed a neuromyopathy.</...

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Bibliographic Details
Main Authors: Steinmetz Sonja, Tipold Andrea, Bilzer Thomas, Schenk Henning
Format: Article
Language:English
Published: BMC 2012-12-01
Series:Irish Veterinary Journal
Subjects:
Epilepsy
Intoxication
Lower motor neuron signs
Myopathy
Potassium bromide
Online Access:http://www.irishvetjournal.org/content/65/1/19
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spelling doaj-10492ee4e0774de4b97c29ee899a05f12020-11-25T00:55:22ZengBMCIrish Veterinary Journal2046-04812012-12-016511910.1186/2046-0481-65-19Transient neuromyopathy after bromide intoxication in a dog with idiopathic epilepsySteinmetz SonjaTipold AndreaBilzer ThomasSchenk Henning<p>Abstract</p> <p>A seven-year old Australian Shepherd, suffering from idiopathic epilepsy under treatment with phenobarbitone and potassium bromide, was presented with generalised lower motor neuron signs. Electrophysiology and muscle-nerve biopsies revealed a neuromyopathy.</p> <p>The serum bromide concentration was increased more than two-fold above the upper reference value.</p> <p>Clinical signs disappeared after applying diuretics and reducing the potassium bromide dose rate. This is the first case report describing electrophysiological and histopathological findings associated with bromide induced lower motor neuron dysfunction in a dog.</p> http://www.irishvetjournal.org/content/65/1/19EpilepsyIntoxicationLower motor neuron signsMyopathyPotassium bromide
collection DOAJ
language English
format Article
sources DOAJ
author Steinmetz Sonja
Tipold Andrea
Bilzer Thomas
Schenk Henning
spellingShingle Steinmetz Sonja
Tipold Andrea
Bilzer Thomas
Schenk Henning
Transient neuromyopathy after bromide intoxication in a dog with idiopathic epilepsy
Irish Veterinary Journal
Epilepsy
Intoxication
Lower motor neuron signs
Myopathy
Potassium bromide
author_facet Steinmetz Sonja
Tipold Andrea
Bilzer Thomas
Schenk Henning
author_sort Steinmetz Sonja
title Transient neuromyopathy after bromide intoxication in a dog with idiopathic epilepsy
title_short Transient neuromyopathy after bromide intoxication in a dog with idiopathic epilepsy
title_full Transient neuromyopathy after bromide intoxication in a dog with idiopathic epilepsy
title_fullStr Transient neuromyopathy after bromide intoxication in a dog with idiopathic epilepsy
title_full_unstemmed Transient neuromyopathy after bromide intoxication in a dog with idiopathic epilepsy
title_sort transient neuromyopathy after bromide intoxication in a dog with idiopathic epilepsy
publisher BMC
series Irish Veterinary Journal
issn 2046-0481
publishDate 2012-12-01
description <p>Abstract</p> <p>A seven-year old Australian Shepherd, suffering from idiopathic epilepsy under treatment with phenobarbitone and potassium bromide, was presented with generalised lower motor neuron signs. Electrophysiology and muscle-nerve biopsies revealed a neuromyopathy.</p> <p>The serum bromide concentration was increased more than two-fold above the upper reference value.</p> <p>Clinical signs disappeared after applying diuretics and reducing the potassium bromide dose rate. This is the first case report describing electrophysiological and histopathological findings associated with bromide induced lower motor neuron dysfunction in a dog.</p>
topic Epilepsy
Intoxication
Lower motor neuron signs
Myopathy
Potassium bromide
url http://www.irishvetjournal.org/content/65/1/19
work_keys_str_mv AT steinmetzsonja transientneuromyopathyafterbromideintoxicationinadogwithidiopathicepilepsy
AT tipoldandrea transientneuromyopathyafterbromideintoxicationinadogwithidiopathicepilepsy
AT bilzerthomas transientneuromyopathyafterbromideintoxicationinadogwithidiopathicepilepsy
AT schenkhenning transientneuromyopathyafterbromideintoxicationinadogwithidiopathicepilepsy
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