Enhanced interleukin-1 activity contributes to exercise intolerance in patients with systolic heart failure.

Enhanced interleukin-1 activity contributes to exercise intolerance in patients with systolic heart failure.

Heart failure (HF) is a complex clinical syndrome characterized by impaired cardiac function and poor exercise tolerance. Enhanced inflammation is associated with worsening outcomes in HF patients and may play a direct role in disease progression. Interleukin-1β (IL-1β) is a pro-inflammatory cytokin...

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Bibliographic Details
Main Authors:	Benjamin W Van Tassell, Ross A Arena, Stefano Toldo, Eleonora Mezzaroma, Tania Azam, Ignacio M Seropian, Keyur Shah, Justin Canada, Norbert F Voelkel, Charles A Dinarello, Antonio Abbate
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2012-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3306393?pdf=render

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