Effect of Probiotic Administration on Serum Tryptophan Metabolites in Pediatric Type 1 Diabetes Patients
Type 1 diabetes (T1D) is characterized by anomalous functioning of the immuno regulatory, tryptophan-catabolic enzyme indoleamine 2,3 dioxygenase 1 (IDO1). In T1D, the levels of kynurenine—the first byproduct of tryptophan degradation via IDO1—are significantly lower than in nondiabetic controls, su...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2020-09-01
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Series: | International Journal of Tryptophan Research |
Online Access: | https://doi.org/10.1177/1178646920956646 |