Application of novel nanomagnetic metal–organic frameworks as a catalyst for the synthesis of new pyridines and 1,4-dihydropyridines via a cooperative vinylogous anomeric based oxidation

Application of novel nanomagnetic metal–organic frameworks as a catalyst for the synthesis of new pyridines and 1,4-dihydropyridines via a cooperative vinylogous anomeric based oxidation

Abstract Herein, a new magnetic metal–organic frameworks based on Fe3O4 (NMMOFs) with porous and high surface area materials were synthesized. Then, NMMOFs were characterized by FT-IR, XRD, SEM, elemental mapping, energy dispersive X-ray (EDS), TG, DTG, VSM, and N2 adsorption–desorption isotherms (B...

Full description

Bibliographic Details
Main Authors: Hassan Sepehrmansourie, Mahmoud Zarei, Mohammad Ali Zolfigol, Saeed Babaee, Sadegh Rostamnia
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-84005-2
id doaj-10334d1bab9b4770a0ae60781d81a0dd
record_format Article
spelling doaj-10334d1bab9b4770a0ae60781d81a0dd2021-03-11T12:13:26ZengNature Publishing GroupScientific Reports2045-23222021-03-0111111510.1038/s41598-021-84005-2Application of novel nanomagnetic metal–organic frameworks as a catalyst for the synthesis of new pyridines and 1,4-dihydropyridines via a cooperative vinylogous anomeric based oxidationHassan Sepehrmansourie0Mahmoud Zarei1Mohammad Ali Zolfigol2Saeed Babaee3Sadegh Rostamnia4Department of Organic Chemistry, Faculty of Chemistry, Bu-Ali Sina UniversityDepartment of Organic Chemistry, Faculty of Chemistry, Bu-Ali Sina UniversityDepartment of Organic Chemistry, Faculty of Chemistry, Bu-Ali Sina UniversityDepartment of Organic Chemistry, Faculty of Chemistry, Bu-Ali Sina UniversityOrganic and Nano Group (ONG), Department of Chemistry, Iran University of Science and Technology (IUST)Abstract Herein, a new magnetic metal–organic frameworks based on Fe3O4 (NMMOFs) with porous and high surface area materials were synthesized. Then, NMMOFs were characterized by FT-IR, XRD, SEM, elemental mapping, energy dispersive X-ray (EDS), TG, DTG, VSM, and N2 adsorption–desorption isotherms (BET). Fe3O4@Co(BDC)-NH2 as a magnetic porous catalyst was applied for synthesis of novel fused pyridines and 1,4-dihydropyridines with pyrazole and pyrimidine moieties as suitable drug candidates under ultrasonic irradiation. The significant advantages of the presented methodology are mild, facile workup, high yields, short reaction times, high thermal stability, and reusability of the described NMMOFs catalyst.https://doi.org/10.1038/s41598-021-84005-2
collection DOAJ
language English
format Article
sources DOAJ
author Hassan Sepehrmansourie
Mahmoud Zarei
Mohammad Ali Zolfigol
Saeed Babaee
Sadegh Rostamnia
spellingShingle Hassan Sepehrmansourie
Mahmoud Zarei
Mohammad Ali Zolfigol
Saeed Babaee
Sadegh Rostamnia
Application of novel nanomagnetic metal–organic frameworks as a catalyst for the synthesis of new pyridines and 1,4-dihydropyridines via a cooperative vinylogous anomeric based oxidation
Scientific Reports
author_facet Hassan Sepehrmansourie
Mahmoud Zarei
Mohammad Ali Zolfigol
Saeed Babaee
Sadegh Rostamnia
author_sort Hassan Sepehrmansourie
title Application of novel nanomagnetic metal–organic frameworks as a catalyst for the synthesis of new pyridines and 1,4-dihydropyridines via a cooperative vinylogous anomeric based oxidation
title_short Application of novel nanomagnetic metal–organic frameworks as a catalyst for the synthesis of new pyridines and 1,4-dihydropyridines via a cooperative vinylogous anomeric based oxidation
title_full Application of novel nanomagnetic metal–organic frameworks as a catalyst for the synthesis of new pyridines and 1,4-dihydropyridines via a cooperative vinylogous anomeric based oxidation
title_fullStr Application of novel nanomagnetic metal–organic frameworks as a catalyst for the synthesis of new pyridines and 1,4-dihydropyridines via a cooperative vinylogous anomeric based oxidation
title_full_unstemmed Application of novel nanomagnetic metal–organic frameworks as a catalyst for the synthesis of new pyridines and 1,4-dihydropyridines via a cooperative vinylogous anomeric based oxidation
title_sort application of novel nanomagnetic metal–organic frameworks as a catalyst for the synthesis of new pyridines and 1,4-dihydropyridines via a cooperative vinylogous anomeric based oxidation
publisher Nature Publishing Group
series Scientific Reports
issn 2045-2322
publishDate 2021-03-01
description Abstract Herein, a new magnetic metal–organic frameworks based on Fe3O4 (NMMOFs) with porous and high surface area materials were synthesized. Then, NMMOFs were characterized by FT-IR, XRD, SEM, elemental mapping, energy dispersive X-ray (EDS), TG, DTG, VSM, and N2 adsorption–desorption isotherms (BET). Fe3O4@Co(BDC)-NH2 as a magnetic porous catalyst was applied for synthesis of novel fused pyridines and 1,4-dihydropyridines with pyrazole and pyrimidine moieties as suitable drug candidates under ultrasonic irradiation. The significant advantages of the presented methodology are mild, facile workup, high yields, short reaction times, high thermal stability, and reusability of the described NMMOFs catalyst.
url https://doi.org/10.1038/s41598-021-84005-2
work_keys_str_mv AT hassansepehrmansourie applicationofnovelnanomagneticmetalorganicframeworksasacatalystforthesynthesisofnewpyridinesand14dihydropyridinesviaacooperativevinylogousanomericbasedoxidation
AT mahmoudzarei applicationofnovelnanomagneticmetalorganicframeworksasacatalystforthesynthesisofnewpyridinesand14dihydropyridinesviaacooperativevinylogousanomericbasedoxidation
AT mohammadalizolfigol applicationofnovelnanomagneticmetalorganicframeworksasacatalystforthesynthesisofnewpyridinesand14dihydropyridinesviaacooperativevinylogousanomericbasedoxidation
AT saeedbabaee applicationofnovelnanomagneticmetalorganicframeworksasacatalystforthesynthesisofnewpyridinesand14dihydropyridinesviaacooperativevinylogousanomericbasedoxidation
AT sadeghrostamnia applicationofnovelnanomagneticmetalorganicframeworksasacatalystforthesynthesisofnewpyridinesand14dihydropyridinesviaacooperativevinylogousanomericbasedoxidation
_version_ 1724224548894670848

Similar Items