Innate Immune Responses to Wildtype and Attenuated Sheeppox Virus Mediated Through RIG-1 Sensing in PBMC In-Vitro

Innate Immune Responses to Wildtype and Attenuated Sheeppox Virus Mediated Through RIG-1 Sensing in PBMC In-Vitro

Sheeppox (SPP) is a highly contagious disease of small ruminants caused by sheeppox virus (SPPV) and predominantly occurs in Asia and Africa with significant economic losses. SPPV is genetically and immunologically closely related to goatpox virus (GTPV) and lumpy skin disease virus (LSDV), which in...

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Bibliographic Details
Main Authors: Tesfaye Rufael Chibssa, Richard Thiga Kangethe, Francisco J. Berguido, Tirumala Bharani K. Settypalli, Yang Liu, Reingard Grabherr, Angelika Loitsch, Elena Lucia Sassu, Rudolf Pichler, Giovanni Cattoli, Adama Diallo, Viskam Wijewardana, Charles Euloge Lamien
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
gene expression
PRRs
cytokine
RIG-1
LAV
SPPV
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.666543/full

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