Inhibition of Morphine- and Ethanol-Mediated Stimulation of Mesolimbic Dopamine Neurons by Withania somnifera

Inhibition of Morphine- and Ethanol-Mediated Stimulation of Mesolimbic Dopamine Neurons by Withania somnifera

Morphine- and ethanol-induced stimulation of neuronal firing of ventral tegmental area (VTA) dopaminergic neurons and of dopamine (DA) transmission in the shell of the nucleus accumbens (AcbSh) represents a crucial electrophysiological and neurochemical response underlying the ability of these compo...

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Bibliographic Details
Main Authors: Valentina Bassareo, Giuseppe Talani, Roberto Frau, Simona Porru, Michela Rosas, Sanjay B. Kasture, Alessandra T. Peana, Eleonora Loi, Enrico Sanna, Elio Acquas
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Neuroscience
Subjects:
dopamine
ethanol
morphine
nucleus accumbens shell
standardized Withania somnifera extract
ventral tegmental area
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00545/full

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