Heart rate modulation in stable coronary artery disease without clinical heart failure: What we have already learned from SIGNIFY?
An elevated heart rate is a marker of cardiovascular risk in patients with stable coronary artery disease. Ivabradine selectively inhibits the “f” current in the sinus node and reduces heart rate without any modifications of blood pressure, myocardial contractility and arteriolar resistance. However...
Main Authors: | Gian Piero Perna, Fabio Vagnarelli, Maurizio Volterrani, Ilaria Battistoni, Claudio Rapezzi |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-12-01
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Series: | Contemporary Clinical Trials Communications |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2451865415300247 |
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