Heart rate modulation in stable coronary artery disease without clinical heart failure: What we have already learned from SIGNIFY?

An elevated heart rate is a marker of cardiovascular risk in patients with stable coronary artery disease. Ivabradine selectively inhibits the “f” current in the sinus node and reduces heart rate without any modifications of blood pressure, myocardial contractility and arteriolar resistance. However...

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Bibliographic Details
Main Authors: Gian Piero Perna, Fabio Vagnarelli, Maurizio Volterrani, Ilaria Battistoni, Claudio Rapezzi
Format: Article
Language:English
Published: Elsevier 2016-12-01
Series:Contemporary Clinical Trials Communications
Online Access:http://www.sciencedirect.com/science/article/pii/S2451865415300247

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