Determination antimicrobial resistance profile of Acinetobacter strains isolated from hospitalized patients in Different Part of Taleghani Hospital (Ahvaz, Iran)

• Main Authors: Khadijah Ahmadi, Jalal Mardaneh, Sareh Saadat
• Format: Article
• Language: English
• Published: Bushehr University of Medical Sciences 2014-10-01
• Series: Iranian South Medical Journal
• Subjects: Acinetobacter spp.; hospital; antibiotic resistance.
• Online Access: http://ismj.bpums.ac.ir/browse.php?a_code=A-10-3-494&slc_lang=en&sid=1
• ISSN: 1735-4374; 1735-6954

Background: The members of the genus Acinetobacter are Gram-negative cocobacilli that are frequently found in the environment but also in the hospital setting where they have been associated with outbreaks of nosocomial infections such as meningitis, endocarditis, skin and soft tissue infections, urinary tract infection, conjunctivitis, burn wound infection and bacteremia. This organism has been shown resistance to different antimicrobial agents. The aim of this study was to determination antibiotic resistance profile of Acinetobacter strains isolated from hospitalized patients in Taleghani hospital (Ahvaz, Iran). Materials and Methods: This cross-sectional study was conducted on 43 Acinetobacter strains isolated from hospitalized patients. Clinical specimens were cultured on microbiological media. Subsequently, drug susceptibility test was performed using the disc diffusion method according to CLSI recommendations. Results: Acinetobacter strains were isolated from different specimens consisting biopsy 24 (55.8%), wound 13 (30/2%) and blood 6 (14%). In antimicrobial susceptibility testing, colistin exhibited the greatest activity (60.5%) against isolated strains. 33 (76/7%) isolates demonstrated resistance to imipenem. Conclusion: In outbreak situations, surveillance cultures of patients involved in the outbreak or who are deemed at risk for colonization/infection with the outbreak organism are often parts of the planned intervention.