Phosphocholine-specific antibodies improve T-dependent antibody responses against OVA encapsulated into phosphatidylcholine-containing liposomes.

Phosphocholine-specific antibodies improve T-dependent antibody responses against OVA encapsulated into phosphatidylcholine-containing liposomes.

Liposomes containing phosphatidylcholine have been widely used as adjuvants. Recently, we demonstrated that B-1 cells produce dipalmitoyl phosphatidylcholine (DPPC)-specific IgM upon immunization of BALB/c mice with DPPC-liposomes encapsulating ovalbumin (OVA). Although this preparation enhanced the...

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Bibliographic Details
Main Authors: Yoelys Cruz-Leal, Alejandro Lopez-Requena, Isbel Lopetegui-González, Yoan Javier Machado Hernández, Carlos Alvarez, Rolando Pérez Rodríguez, Maria Eliana Lanio
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Immunology
Subjects:
Liposomes
B-1 cells
humoral response
peritoneal macrophages
phosphocholine-specific antibodies
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00374/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00374/full

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