Increased Risk of Multiple Outpatient Surgeries in African-American Carriers of <i>Transthyretin</i> Val122Ile Mutation Is Modulated by Non-Coding Variants

Increased Risk of Multiple Outpatient Surgeries in African-American Carriers of <i>Transthyretin</i> Val122Ile Mutation Is Modulated by Non-Coding Variants

<b>Background:</b> African-Americans (AAs) have a 3.5% carrier prevalence of <i>Transthyretin</i> (<i>TTR</i>) Val122Ile mutation (rs76992529), which is the genetic cause of a hereditary form of amyloidosis. <b>Methods</b>: We investigated the medical...

Full description

Bibliographic Details
Main Authors: Renato Polimanti, Yaira Z. Nuñez, Joel Gelernter
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Journal of Clinical Medicine
Subjects:
TTR amyloidosis
African ancestry
phenome-wide
V122I
medical history
Online Access:https://www.mdpi.com/2077-0383/8/2/269

Similar Items

Similar Items