MiR-218 inhibits invasion and metastasis of gastric cancer by targeting the Robo1 receptor.

MiR-218 inhibits invasion and metastasis of gastric cancer by targeting the Robo1 receptor.

MicroRNAs play key roles in tumor metastasis. Here, we describe the regulation and function of miR-218 in gastric cancer (GC) metastasis. miR-218 expression is decreased along with the expression of one of its host genes, Slit3 in metastatic GC. However, Robo1, one of several Slit receptors, is nega...

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Bibliographic Details
Main Authors: Jun Tie, Yanglin Pan, Lina Zhao, Kaichun Wu, Jie Liu, Shiren Sun, Xuegang Guo, Biaoluo Wang, Yi Gang, Yongguo Zhang, Quanjiang Li, Taidong Qiao, Qingchuan Zhao, Yongzhan Nie, Daiming Fan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2837402?pdf=render

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