Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain
There are only a few examples of nanocarriers that can transport bioactive substances across the blood-brain barrier. Here the authors show that by rapid glycaemic increase the accumulation of a glucosylated nanocarrier in the brain can be controlled.
Bibliographic Details
Main Authors: |
Y. Anraku,
H. Kuwahara,
Y. Fukusato,
A. Mizoguchi,
T. Ishii,
K. Nitta,
Y. Matsumoto,
K. Toh,
K. Miyata,
S. Uchida,
K. Nishina,
K. Osada,
K. Itaka,
N. Nishiyama,
H. Mizusawa,
T. Yamasoba,
T. Yokota,
K. Kataoka |
Format: | Article
|
Language: | English |
Published: |
Nature Publishing Group
2017-10-01
|
Series: | Nature Communications
|
Online Access: | https://doi.org/10.1038/s41467-017-00952-3
|