Transplantation of bone marrow derived macrophages reduces markers of neuropathology in an APP/PS1 mouse model

Transplantation of bone marrow derived macrophages reduces markers of neuropathology in an APP/PS1 mouse model

Abstract Background We investigated early hallmarks of putative therapeutic effects following systemic transplantation of bone marrow derived macrophages (BM-M) in APP/PS1 transgenic mice. Method BM-M were transplanted into the tail vein and the animals analysed 1 month later. Results BM-M transplan...

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Bibliographic Details
Main Authors: Luís Costa-Marques, Katrin Arnold, Marie-Christine Pardon, Christiane Leovsky, Samantha Swarbrick, Claire Fabian, Alexandra Stolzing
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Translational Neurodegeneration
Subjects:
Amyloid beta
Microglia
Alzheimer’s disease
Cell therapy
Neuroinflammation
Online Access:http://link.springer.com/article/10.1186/s40035-019-0173-9

Internet

http://link.springer.com/article/10.1186/s40035-019-0173-9

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