LUNG CLEAR “SUGAR” CELL TUMOR AND JAK V617F POSITIVE ESSENTIAL THROMBOCYTHEMIA: COINCIDENCE

• Main Authors: Volkan Yazak, Gokhan Sargin, Irfan Yavasoglu, Gurhan Kadikoylu, Canten Tataroglu, Gokay Bozkurt, Zahit Bolaman
• Format: Article
• Language: English
• Published: PAGEPress Publications 2014-08-01
• Series: Mediterranean Journal of Hematology and Infectious Diseases
• Subjects: Lung Clear “Sugar” Cell Tumor; Essential Thrombocythemia; JAK V617F
• Online Access: https://mjhid.org/index.php/mjhid/article/view/1858

The primary clear cell tumor of the lung is an extremely rare benign tumor. This tumor is called “sugar tumor”. Because, clear cell tumor of the lung contains abundant glycogen. We present here a case of lung clear cell tumor of the lung with essential thrombocythemia. To the best of our knowledge, there is no report about this entite. A 44-Year-Old Woman admitted to our clinic with a 2-month history of fatigue. On pathological examination, the spleen was 3 cm palpable below the left costal margin on the mid axillary line. The laboratory tests revealed an elevated platelet counts (1,014,000/mm³). A pulmonary nodule (3,5 cm) was detected in the upper right lobe on the chest X-ray. Then, thoracic computed tomography (CT ) was planned. The nodule looked like bening pattern on CT scan and total excision was performed for curative and diagnostic treatment. Microscopically, the tumor was composed of nests of rounded or oval cells with distinct cell borders, optically clear cytoplasm and small nucleus. By immunohistochemistry, tumor cells were positive for HMB-45, NSE and focal S100 antigen. And, it was diagnosed as clear “sugar” cell tumor. In conclusion, it is important to make an evaluation for myeloproliferative diseases and suspected clear “sugar” cell tumor in adults if thrombocytosis was continued after treatment.