Disulfides from the Brown Alga <i>Dictyopteris Membranacea</i> Suppress M1 Macrophage Activation by Inducing AKT and Suppressing MAPK/ERK Signaling Pathways

Disulfides from the Brown Alga <i>Dictyopteris Membranacea</i> Suppress M1 Macrophage Activation by Inducing AKT and Suppressing MAPK/ERK Signaling Pathways

Inflammation is part of the organism’s response to deleterious stimuli, such as pathogens, damaged cells, or irritants. Macrophages orchestrate the inflammatory response obtaining different activation phenotypes broadly defined as M1 (pro-inflammatory) or M2 (homeostatic) phenotypes, which contribut...

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Bibliographic Details
Main Authors: Maria G. Daskalaki, Paraskevi Bafiti, Stefanos Kikionis, Maria Laskou, Vassilios Roussis, Efstathia Ioannou, Sotirios C. Kampranis, Christos Tsatsanis
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Marine Drugs
Subjects:
<i>Dictyopteris membranacea</i>
disulfides
macrophages
inflammation
TNFα
iNOS
Online Access:https://www.mdpi.com/1660-3397/18/11/527

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