T-Cell Production of Matrix Metalloproteinases and Inhibition of Parasite Clearance by TIMP-1 During Chronic Infection in the Brain
Chronic infection with the intracellular protozoan parasite Toxoplasma gondii leads to tissue remodelling in the brain and a continuous requirement for peripheral leucocyte migration within the CNS (central nervous system). In the present study, we investigate the role of MMPs (matrix metalloprotein...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2010-12-01
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| Series: | ASN Neuro |
| Online Access: | https://doi.org/10.1042/AN20100027 |