Abscisic acid regulates dormancy of prostate cancer disseminated tumor cells in the bone marrow

Abscisic acid regulates dormancy of prostate cancer disseminated tumor cells in the bone marrow

Prostate cancer (PCa) commonly metastasizes to the bone where the cells frequently undergo dormancy. The escape of disseminated tumor cells from cellular dormancy is a major cause of recurrence in marrow. Abscisic acid (ABA), a phytohormone, is known to regulate dormancy of plant seeds and to regula...

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Bibliographic Details
Main Authors: Younghun Jung, Frank C. Cackowski, Kenji Yumoto, Ann M. Decker, Yu Wang, Megan Hotchkin, Eunsohl Lee, Laura Buttitta, Russell S. Taichman
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Prostate cancer
Disseminated tumor cells
Dormancy
Abscisic acid
PPARγ
Bone marrow microenvironment
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558620301779

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