Genetic interplay between transcription factor Pou4f1/Brn3a and neurotrophin receptor Ret in retinal ganglion cell type specification

Abstract Background While the transcriptional code governing retinal ganglion cell (RGC) type specification begins to be understood, its interplay with neurotrophic signaling is largely unexplored. In mice, the transcription factor Brn3a/Pou4f1 is expressed in most RGCs, and is required for the spec...

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Bibliographic Details
Main Authors: Vladimir Vladimirovich Muzyka, Tudor Constantin Badea
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Neural Development
Subjects:
Ret
Online Access:https://doi.org/10.1186/s13064-021-00155-z