Host-pathogen interactions between the human innate immune system and Candida albicans - Understanding and modeling defense and evasion strategies

Host-pathogen interactions between the human innate immune system and Candida albicans - Understanding and modeling defense and evasion strategies

The diploid, polymorphic yeast Candida albicans is one of the most important humanpathogenic fungi. C. albicans can grow, proliferate and coexist as a commensal on or within thehuman host for a long time. Alterations in the host environment, however, can render C. albicansvirulent. In this review, w...

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Bibliographic Details
Main Authors: Sybille eDühring, Sebastian eGermerodt, Christine eSkerka, Peter F. Zipfel, Thomas eDandekar, Stefan eSchuster
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-06-01
Series:Frontiers in Microbiology
Subjects:
Candida albicans
host-pathogen interaction
Computational systems biology
human immune system
immunological cross-talk
defense and evasion strategies
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00625/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00625/full

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