Autophagy plays a protective role in advanced glycation end products- induced apoptosis of chondrocytes via regulation of tumor necrosis factor-α , nuclear factor-κ B and reactive oxygen species

Autophagy plays a protective role in advanced glycation end products- induced apoptosis of chondrocytes via regulation of tumor necrosis factor-α , nuclear factor-κ B and reactive oxygen species

Objective: To study the adverse effects of advanced glycation end products (AGEs) on chondrocytes and the role of autophagy in this process. Methods: Chondrocytes were harvested from the human articular cartilage tissues in surgery. AGEs were administered during chondrocytes culture. The rapamycin w...

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Bibliographic Details
Main Authors: Zhi-Jiang Sun, Ya-Yi Xia
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Asian Pacific Journal of Tropical Medicine
Subjects:
advanced glycation end products
autophagy
tumor necrosis factor- α
nuclear factor- κ b
reactive oxygen species
apoptosis
chondrocytes
Online Access:http://www.apjtm.org/article.asp?issn=1995-7645;year=2018;volume=11;issue=1;spage=73;epage=77;aulast=Sun

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