Interleukin-1β and interleukin-6 gene polymorphisms in Egyptian sickle cell disease patients

Interleukin-1β and interleukin-6 gene polymorphisms in Egyptian sickle cell disease patients

Abstract Background Sickle cell disease (SCD) is a disorder characterized by a heterogeneous clinical outcome. Interleukin-1β (IL-1β) and interleukin-6 (IL-6) are important mediators of inflammatory response. Genetic modifiers that alter cytokine levels may contribute to the clinical variability of...

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Bibliographic Details
Main Authors: Yasmine Elammary, Nadia Sewelam, Hanan Al-Wakeel, Mona El-Ghamrawy, Shahira Zayed
Format: Article
Language:English
Published: SpringerOpen 2020-05-01
Series:Egyptian Pediatric Association Gazette
Subjects:
IL-1β (+ 3954 C>T)
IL-6 (− 174G>C)
IL-6 (− 597G>A)
Polymorphism
Sickle cell disease
Online Access:http://link.springer.com/article/10.1186/s43054-020-00025-z

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http://link.springer.com/article/10.1186/s43054-020-00025-z

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