Toll-like receptor 4 upregulation by angiotensin II contributes to hypertension and vascular dysfunction through reactive oxygen species production.

Toll-like receptor 4 upregulation by angiotensin II contributes to hypertension and vascular dysfunction through reactive oxygen species production.

Hypertension is considered as a low-grade inflammatory disease, with adaptive immunity being an important mediator of this pathology. TLR4 may have a role in the development of several cardiovascular diseases; however, little is known about its participation in hypertension. We aimed to investigate...

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Bibliographic Details
Main Authors: Priscila R De Batista, Roberto Palacios, Angela Martín, Raquel Hernanz, Cindy T Médici, Marito A S C Silva, Emilly M Rossi, Andrea Aguado, Dalton V Vassallo, Mercedes Salaices, María J Alonso
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4122400?pdf=render

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